Facebook Twitter Instagram
    Facebook Instagram Twitter YouTube LinkedIn
    Dr David Marlin
    Header image
    • News
      1. News
      2. Blog
      Featured
      4 May 2022

      Marlin and members test acoustic ears/earplugs/noise-cancelling bonnets/fly veils

      Recent
      20 May 2022

      We must work with Vets to tackle anthelmintic resistance

      18 May 2022

      Acoustic ears and ear bonnets – The test results will be released Thursday night.

      9 May 2022

      Amazing line-up for Queen’s Platinum Jubilee Celebration at RWHS

    • Resources
      • Articles
      • Product Reviews
      • How To
      • Feed Materials In Focus
      • Research/Papers
        • Research Reviewed
      • References
      • Glossary
    • Webinars
      • Upcoming
      • Previous
    • Podcasts/Videos
      • Podcasts
      • Videos
    • What’s On
    • Website Guide
      • Guide to the Site
      • Why Join?
      • Become a Member
      • About Dr David Marlin
      • Our Team
      • FAQs
      • Services & Contact
    • Members Area
      • Your Membership
        • Manage Your Subscriptions
        • Edit Your Details
        • Renew Here
      • Member Offers
      • Member’s Questions
    • Log In
    Dr David Marlin
    You are at:Home»News»Latest study suggests there is a way to test for diagnosing gastric ulcers through saliva
    Scientist researching the impact of sex of handlers and riders

    Latest study suggests there is a way to test for diagnosing gastric ulcers through saliva

    0
    By Helen Stock on 3 May 2022 News

    This study based in Zagreb in Croatia detected differences in the salivary and serum proteome between horses with EGUS and healthy horses, and also between horses with EGGD and ESGD.

    The most upregulated proteins in EGGD were related to the immune activation whereas, in horses with ESGD, the proteins with the most significant changes were associated with the squamous cell regulation and growth. Compared to serum, saliva had a higher number of proteins showing significant changes and also showed a different pattern of changes, indicating that the proteins in both fluids show a different response to the disease and can provide complementary information.

    Below is an abstract of the study.

    Abstract
    Changes in the salivary proteome in 12 horses with the two diseases included in equine gastric ulcer syndrome (EGUS), equine glandular gastric disease (EGGD) (n = 6) and equine squamous gastric disease (ESGD) (n = 6), were evaluated using a high-resolution LC-MS/MS analysis of TMT-labelled peptides and compared to 10 healthy control horses. Serum was also analysed for comparative purposes. The comparison between the horses with EGGD and controls showed significant changes in 10 salivary proteins, whereas 36 salivary proteins were differently abundant between ESGD and control groups. The most upregulated proteins in the case of EGGD were related to immune activation whereas, in horses with ESGD, the most significantly changed proteins were associated with squamous cell regulation and growth. Compared to serum, saliva showed a higher number of proteins with significant changes and a different pattern of changes. The proteins identified in our study, in addition to providing new information about the pathophysiological mechanisms in these diseases, could have the potential to be novel biomarkers for the diagnosis or monitoring of EGGD and ESGD.

    To learn more about this study follow this link to an Open Access Article on the Changes in Proteins in Saliva and Serum in Equine Gastric Ulcer Syndrome Using a Proteomic Approach

    Related posts:

    1. EGUS – Equine Gastric Ulcer Syndrome
    2. Equine Gastric Ulcer Syndrome (EGUS)
    3. Research Paper PrePrint – Comparison of stirrup lengths chosen for flatwork by novice and experienced riders
    4. Marlin Scientific References to 2020
    EGGD EGUS ESGD Saliva
    Share. Facebook Twitter Pinterest LinkedIn Tumblr Email
    Helen Stock

    Helen is Head of Operations. Making sure the website and membership runs smoothly, whilst developing new ideas and initiatives.

    Related Posts

    Research Paper PrePrint – Comparison of stirrup lengths chosen for flatwork by novice and experienced riders

    EGUS – Equine Gastric Ulcer Syndrome

    Equine Gastric Ulcer Syndrome (EGUS)

    Introduction from David
    https://vimeo.com/478007186?loop=0
    Popular Posts
    • Ollie Townend riding Ballaghmor Class during the Tokyo 2020 OlympicsDavid’s Diary from Tokyo – 2/08/21
      In Blog
      2 August 2021
    • AlfalfaAlfalfa allergy and intolerance – is it real or another Facebook myth and marketing trick?
      In Feed Materials In Focus
      14 March 2021
    • Sarcoids with Dr kirstie PicklesWebinar – Sarcoids by Dr Kirstie Pickles
      In Webinars, Webinars/Vids/Pods
      19 February 2022
    • Badminton Horse Trials 2022 – Dressage science
      In News
      5 May 2022
    • Wellington Boot Survey Released and it’s Full of Surprises!
      In News
      12 December 2020
    • Webinar – Mark Fisher Team GB Master Saddler and Fitter
      In Webinars, Webinars/Vids/Pods
      19 May 2021
    Join Now Banner
    About

    The drdavidmarlin.com site is an independent information resource for all equestrians. A source of unbiased, science-based research, we deliver news, and product reviews, with webinars, podcasts and articles covering the full breadth of the equine world.

    David Marlin has been involved with horses all his life and is an experienced equine scientist. He has always been passionate about equine welfare and as a result has been involved in many campaigns. You can read more about David in the About Page.

    Become a member today to get access to all this site has to offer!

    Become a Member

      Facebook Twitter Instagram YouTube LinkedIn
      Copyright © 2022 Dr David Marlin
      • How To Join
      • Website User Guide
      • FAQs
      • Services & Contact
      • Legal – Disclaimers, Terms, and Policies
      • Sitemap

      Type above and press Enter to search. Press Esc to cancel.

      We are using cookies to give you the best experience on our website.

      You can find out more about which cookies we are using or switch them off in settings.

      Dr David Marlin
      Powered by  GDPR Cookie Compliance
      Privacy Overview

      This website uses cookies so that we can provide you with the best user experience possible. Cookie information is stored in your browser and performs functions such as recognising you when you return to our website and helping our team to understand which sections of the website you find most interesting and useful.

      Strictly Necessary Cookies

      Strictly Necessary Cookie should be enabled at all times so that we can save your preferences for cookie settings.

      If you disable this cookie, we will not be able to save your preferences. This means that every time you visit this website you will need to enable or disable cookies again.